How do bacteria sense changes in their environment? How do they respond and adapt to different stresses such as exposure to antimicrobial agents?
The Yadavalli lab is interested in understanding the regulatory pathways that underlie stress response in bacteria and how these pathways contribute to the emergence of antimicrobial resistance. In addition, my lab will explore the biochemical functions of the growing number of understudied small proteins - a challenging yet exciting new area in bacterial gene regulation networks. We use a variety of tools including classical genetics, microbiology, and biochemistry, high throughput sequencing as well as proteomics to answer fundamental questions in bacterial stress response.
We are deeply committed to mentoring students from diverse backgrounds and at all levels of education.
Dr. Srujana Samhita Yadavalli
Waksman Institute of Microbiology
190 Frelinghuysen Road, Room 133
Piscataway, NJ 08854-0753
Dr. Srujana Samhita Yadavalli is an assistant professor of graduate studies in the Genetics Department and lab director at the Institute. Her new assignment begins on September 1, 2019. In her new role, she plans to develop an interdisciplinary research program to study how bacteria respond to and evolve resistance to antimicrobial stress. In addition, her research will highlight the biochemical functions of the growing number of understudied small proteins and provide insights into a new and emerging theme of gene expression regulation. She is also deeply committed to mentoring students from diverse backgrounds and at all levels of education.
For the past 2 years, Dr. Yadavalli has worked as a Research Associate integrating tools from microbiology, biochemistry, and genetics to understand bacterial gene regulatory networks underlying stress response in the Bryce Nickels Lab. Prior to joining Rutgers, she worked as a postdoctoral researcher in the Mark Goulian lab at the University of Pennsylvania, studying signal transduction and regulation of gene expression in bacteria. As a doctoral candidate in the Michael Ibba lab, her research helped understand how some PheRS enzymes that lack major quality control mechanisms conserved in E. coli and other bacteria function.