Sarah J. Radford

Post-Doctoral Fellow

Start Date: February 2007

 

Degrees:

B.S. Juniata College (May 2001)

Ph.D. University of North Carolina-Chapel Hill (December 2006)

 

Awards:

Helen Hay Whitney Postdoctoral Fellowship (2008-2011)

Waksman Retreat Travel Award (September 2008)

 

Mentored undergrads: Apple ('08), Andrew ('10), Nismah ('11), Anand ('11), Katie ('12), James ('12), Tran ('13), Allysa ('14), Rachel ('15), Aashka ('16), Laura ('17)

 

Research Summary: I am focused on how chromosomes are segregated via their interactions with microtubules during the acentrosomal meiotic divisions. My work currently centers on the regulation of microtubule dynamics and the role of kinetochores.

 

Publications:

 

Radford, SJ, Go A MM, McKim KS.  2016.  Cooperation Between Kinesin Motors Promotes Spindle Symmetry and Chromosome Organization in Oocytes.Genetics. 

 

Radford, SJ, McKim KS.  2016.  Techniques for Imaging Prometaphase and Metaphase of Meiosis I in Fixed Drosophila Oocytes.Journal of visualized experiments : JoVE. (116)

 

Radford, SJ, Nguyen AL, Schindler K, McKim KS.  2016.  The chromosomal basis of meiotic acentrosomal spindle assembly and function in oocytes.Chromosoma. 

 

Głuszek, AA, Cullen FC, Li W, Battaglia RA, Radford SJ, Costa MF, McKim KS, Goshima G, Ohkura H.  2015.  The microtubule catastrophe promoter Sentin delays stable kinetochore-microtubule attachment in oocytes.The Journal of cell biology. 211(6):1113-20.

  

Radford, SJ, Hoang TL, Gluszek AA, Ohkura H, McKim KS.  2015.  Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes. PLoS Genetics. 11(10):e1005605.

 

Mathieu, J, Cauvin C, Moch C, Radford SJ, Sampaio P, Perdigoto CN, Schweisguth F, Bardin AJ, Sunkel CE, McKim K et al..  2013.  Aurora B and cyclin B have opposite effects on the timing of cytokinesis abscission in Drosophila germ cells and in vertebrate somatic cells. Dev Cell. 26(3):250-65.

 

Radford, SJ, Jang JK, McKim KS.  2012.  The Chromosomal Passenger Complex is required for Meiotic Acentrosomal Spindle Assembly and Chromosome Bi-orientationGenetics. 192:417-429.

 

Radford, SJ, Harrison AM, McKim KS.  2012.  Microtubule-depolymerizing Kinesin KLP10A Restricts the Length of the Acentrosomal Meiotic Spindle in Drosophila FemalesGenetics. 192:431-440.