Barr Project earns award from NIH

Dr. Maureen Barr's  latest award is in support of her lab's human disease research project titled, "Polycystins and Cilia in C. elegans".  In a report earlier this year, she wrote about their initial findings and discoveries. Barr said, "[w]e were the first to discover that the polycystins localized to Cilia, provide an important link between the cilium and human disease. Cilia are cellular organelles that are essential for human development, organ function, fertility, and sensation of touch, sight, smell, taste, and hearing."

According to their website, "the Barr laboratory has well-established C. elegans models for Autosomal Dominant Polycystic Kidney Disease (ADPKD) and Nephronophthisis (NPHP), and is currently developing a worm model for Meckel-Gruber Syndrome (MKS), the leading syndromic cause of neural tube defects in humans. Results of our studies will broaden our understanding of how cilia develop, form, and function in normal and pathological states and provide new insight into the molecular basis of human ciliopathies."

For more information, please visit the Barr Lab.