Richard H. Ebright--Patents

Issued Patents

Ebright, R., Ebright, Y., and Pendergrast, P.S. (1996) CAP-phenanthroline conjugate for DNA cleavage. US Patent 5,556,949.

Seul, M. and Ebright, R. (2003) Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. Australian Patent 756,945.

Ebright, R. and Ebright, Y. (2005) Bis-transition-metal-chelate probes. US Patent 6,919,333.

Seul, M. and Ebright, R. (2006) Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. US Patent 7,083,914.

Ebright, R. and Ebright, Y. (2006) Reagents and procedures for high-specificity labelling. US Patent 7,141,655.

Ebright, R. and Ebright, Y. (2007) Ultra-high-specificity fluorescent labelling. US Patent 7,282,373.

Seul, M. and Ebright, R. (2007) Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. European Patent 1,003,904.

Ebright, R. and Ebright, Y. (2008) Bis-transition-metal-chelate probes. US Patent 7,371,745.

Ebright, R. and Ebright, Y. (2008) Reagents and procedures for multi-label high-specificity labelling. US Patent 7,381,572.

Severinov, K., Ebright, R, Pavlova, O., and Sineva, E. (2008) Mutational derivatives of peptide antibiotic microcin J25. US Patent 7,442,762. 

Seul, M. and Ebright, R. (2009) Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. Japanese Patent 4,302,780.

Ebright, R. (2012) Switch region: target and method for inhibition of bacterial RNA polymerase. US Patent 8,114,583.

Ebright, R. (2012) Target and method for inhibition of bacterial RNA polymerase. US Patent 8,198,021.

Ebright, R. (2012) RNA exit channel: target and method for inhibition of bacterial RNA polymerase. US Patent 8,206,898.

Seul, M. and Ebright, R. (2013) Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. Canadian Patent 2,291,853.

Ebright, R., Mukhopadhyay, J., Severinov, K., and Semenova, E.  (2013) Non-MccJ25-related lariat-peptide inhibitors of bacterial RNA polymerase. US Patent 8,354,246.

Ebright, R. and Wang, D. (2013) Bipartite inhibitors of bacterial RNA polymerase. US Patent 8,372,839.

Ebright, R., and Severinov, K. (2013)  Nucleic acid sequences for biosynthesis of non-MccJ25-related lariat peptides. US Patent 8,461,314.

Ebright, R. (2013) Target and method for inhibition of bacterial RNA polymerase. US Patent 8,575,306.

Ebright, R. (2014) RNA exit channel: target and method for inhibition of bacterial RNA polymerase. US Patent 8,697,354.

Ebright, R.  (2014) Arylpropionyl-alpha-pyrone antibacterial agents. US Patent 8,772,332.

Ebright, R., Degen, D., and Ebright, K. (2015) Bridge-helix cap: target and method for inhibition of bacterial RNA polymerase. US Patent 9,060,970.

Ebright, R. and Ebright, Y. (2015) Antibacterial agents: high-potency myxopyronin derivatives. US Patent 9,133,155.

Ebright, R. and Ebright, Y. (2015) Antibacterial agents: side-chain-fluorinated myxopyronin derivatives. US Patent 9,187,446.

Ebright, R., Ebright, Y., Feng, Y., and Degen, D. (2015) Antibacterial agents: salinamide derivatives. US Patent 9,221,880.

Ebright, R., Feng, Y., and Zhang, Y. (2016) Bipartite inhibitors of bacterial RNA polymerase: Sal-target-inhibitor/nucleoside-analog-inhibitor conjugates. US Patent 9,243,039.

Ebright, R., Ebright, Y., Shen, J., Bacci, J., Hiebel, A.-C., Solvible, W., Self, C., and Olson, G. (2016) Antibacterial agents: aryl myxopyronin derivatives. US Patent 9,315,495.

Ebright, R., Degen, D., Zhang, Y., Ebright, Y. (2016) Bipartite inhibitors of bacterial RNA polymerase. US Patent 9,415,112.

Ebright, R. and Shen, J. (2016) Antibacterial agents: phloroglucinol derivatives. US Patent 9,517,994.

Ebright, R., Ebright, Y., Shen, J., Bacci, J., Hiebel, A.-C., Solvible, W., Self, C., and Olson, G. (2017) Antibacterial agents: aryl myxopyronin derivatives. US Patent 9,592,221.

Ebright, R., Ebright, Y., Feng, Y., and Degen, D.  Antibacterial agents: salinamide derivatives. US Patent 9,605,028.

  

Pending Patents

Ebright, R. and Shen, J.  Arylpropionyl-triketone antibacterial agents. PCT/US11/50708 (filed 09/07/2011; pending).

Ebright, R.  Antibacterial agents: combination of a rifamycin and a switch region inhibitor. PCT/US13/24765 (filed 02/5/2013; pending).

Ebright, R., Ebright, Y., Shen, J., Bacci, J., Hiebel, A.-C., Solvible, W., Self, C., and Olson, G.  Antibacterial agents: aryl myxopyronin derivatives. EP2861570 (filed 06/09/13; pending).

Ebright, R.  Color-encoding and in-situ interrogation of matrix-coupled chemical compounds. US14607496 (filed 01/28/2015; pending).

Ebright, R., Ebright Y., Mandal, S., Wilde, R., and Li, S.  Antibacterial agents: N(alpha)-aroyl-N-aryl-phenylalaninamides. PCT/US15/14899 (filed 02/06/2015; pending).

Ebright, R., Degen, D., and Ebright, K. (2015) Bridge-helix cap: target and method for inhibition of bacterial RNA polymerase. US20160082076 (filed 05/13/2015; pending).

Ebright, R., Degen, D., Zhang, Y., Ebright, Y.  Bipartite inhibitors of bacterial RNA polymerase. US20170056512 (filed 08/15/2016; pending).

Ebright, R., Freundlich, J., Mittal, N., Jaskowski, M, and Shen, J.  Inhibitors of bacterial RNA polymerase: arylpropanoyl, arylpropenoyl, and arylcyclopropanecarboxyl phloroglucinols. PCT/US16/65931 (filed 12/09/16; pending).

Ebright, R., Ebright, Y., Feng, Y., and Degen, D.  Antibacterial agents: salinamide derivatives. US20170166611 (filed 02/17/2017; pending).

 

Dr. Richard H. Ebright