InsertionMapper: a pipeline tool for the identification of targeted sequences from multidimensional high throughput sequencing data.

Xiong, W, He L, Li Y, Dooner HK, Du C.  2013.  

Journal:

BMC genomics

Volume Number:

14

Pages:

679

Abstract:

The advent of next-generation high-throughput technologies has revolutionized whole genome sequencing, yet some experiments require sequencing only of targeted regions of the genome from a very large number of samples. These regions can be amplified by PCR and sequenced by next-generation methods using a multidimensional pooling strategy. However, there is at present no available generalized tool for the computational analysis of target-enriched NGS data from multidimensional pools.
Citation:
Xiong, W, He L, Li Y, Dooner HK, Du C.  2013.  InsertionMapper: a pipeline tool for the identification of targeted sequences from multidimensional high throughput sequencing data.. BMC genomics. 14:679.