Animal Genetics

Shared Genetics in Humans and Roundworms Shed Light on Infertility, Rutgers Study Finds

Shared Genetics in Humans and Roundworms Shed Light on Infertility, Rutgers Study Finds

Discovery could lead to more effective treatments and better contraceptives

Source: Robin Lally - Rutgers Today
Posted: Thursday, December 3, 2015

McKim Lab Postdoc featured in GSA blog

GSA's Spotlight on Undergraduate Research featured Sarah Radford, a Postdoctoral Associate in the McKim Lab.
See the full blog at http://genestogenomes.org/the-impact-of-sarah-radfords-undergraduate-research/

The impact of Sarah Radford's undergraduate research  

How did you become involved in research?              

Dr. Maureen Barr

Principal Investigator

Survival requires strategies to identify and attract mates. How sensory neurons receive sex- specific signals and how multiple sensory stimuli are integrated to produce innate, stereotyped behaviors is poorly understood.

Dr. Ruth Steward

Principal Investigator

The Steward lab has research interests in the Toll-Dorsal (NF-kB/Rel) pathway functioning in establishing dorsal-ventral polarity in the early Drosophila embryo, in the humoral and cellular immune response, and in hematopoiesis.  The pathway is conserved in flies and vertebrates. In mammals it controls the immune and inflammatory responses and is critical for cell growth and survival.

Dr. Andrew Singson

Principal Investigator

Fertilization is a biological process that has important social, economic and medical implications. Our primary research interest is the mechanisms of sperm-egg interactions. The long-term goal of research in the lab is to understand the molecular events that mediate gamete recognition, adhesion, signaling and fusion.

Dr. Christopher Rongo

Principal Investigator

Our research is focused on glutamate receptors, which are ligand-gated channels that mediate much of the excitatory communication between neurons in the brain. The trafficking of these receptors in neurons is thought underly synaptic plasticity, and their inappropriate activation is implicated in several diseases of the nervous system.

Dr. Richard W. Padgett

Principal Investigator

My laboratory is interested in understanding the molecular mechanisms of growth control. Our primary focus is on the transforming growth factor-β-like pathways (TGFβ) in C. elegans and Drosophila.

Dr. Kim S. McKim

Principal Investigator

Meiosis is the process by which the chromosome number is divided precisely in half.  When defects occur in the meiotic process the oocyte or sperm receives an abnormal number of chromosomes (aneuploidy).  Aneuploidy is usually catastrophic and is the leading cause of infertility in women and the cause of disorders such as Down’s syndrome.  Research in my laboratory is directed towards understanding meiosis in the model organism Drosophila melanogaster.  By utilizing the experimental benefits of Drosophila, mutations that disrupt various steps in the meiotic progr

Dr. Kenneth D. Irvine

Principal Investigator

Our current research focusses on a novel signaling pathway, the Fat-Hippo pathway, which play important roles in growth control from Drosophila to humans. We study both the molecular mechanism of Fat-Hippo signaling, and its developmental functions.